Based on 423 reviews, the restaurant has received a rating of 4.5 stars. Price $
✔️ Dine-in ✔️ Takeout ✔️ Delivery
Address:
543 E Main St, Chillicothe, OH 45601
Phone: (740) 774-7827
Social Profile: 
Hours
| Wednesday | 11 AM–10 PM |
| Thursday | 11 AM–10 PM |
| Friday | 11 AM–11 PM |
| Saturday | 11 AM–11 PM |
| Sunday | 11 AM–10 PM |
| Monday | 11 AM–10 PM |
| Tuesday | 11 AM–10 PM |
Menu Photos
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Reviews
Brad Jefferson
We stopped here on our way through town and were pleasantly surprised at how awesome the subs are.
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IRA HILT
Great food. Nice menu. Good prices. Good looking interior. Very impressed. Will definitely go back and recommend to others.
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Jenni
Completely unexpected stop on our road trip and we will be back. Best sub sandwiches ever. Love that you can get them as small as 4″. We also tried the stuffed mushrooms, which were some of the best we’ve ever eaten.
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Donté Dunnagan
Small local spot is becoming my favorite place to eat in town. I am close by this place so it’s an easy choice to pick. Every sub has been consistent with the quality and presentation. The bread is very good. Not burned not under toasted but perfect and holds the sandwich ingredients in place properly. Had the chilli a few times. Very meaty, more so than I expected. Not spicy which is good for someone like me that’s not a fan of spicy food. Highly recommend!
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Joe Watson (Joe Cool)
Mister Sub has moved onto Main Street. Wow!!! Amazing food as usual, but now they have upgraded their restaurant and eat in area. They took over The Mill restaurant and are ready to be amazing. We just ordered a BBQ Chicken 8 inch and the Super Italian 8 inch sub and loved them. With this new location of the dine in restaurant and the same awesome food, I expect that Mister Sub will make more money while attracting new clientele. Definitely check it out, you will not be disappointed.
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Ashley Engelbrecht
A+ i think i just ate the best sandwich I’ve ever had. The bread itself is a phenomenon. I’m on my way back to Chicago and i don’t like fast food so i popped in here for a sub and I’ll probably be thinking about it until i die.
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Sherry Lochner
Oh, wow! Amazing subs! Hubby had the Super Italian and I had the Island Hopper. Great flavor, freshly made, and packed full of yumminess! Great service, too!
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Alessandra Graham
Wonderful food, everything came out quickly and tasted amazing! Great, friendly staff! Will be back again!
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No Body
I’ve been ordering from Mister Sub since they reopened on Main St. and for several years before when they were behind Cardo’s.
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Audra Queen
The food here is absolutely delicious. Buns are made fresh on site. Prices are fair. The food is great but phone staff tend to be rude.
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